Benfotiamine is a derivative of vitamin B1. It was developed in Japan specifically to treat Korsakoff’s syndrome Benfotiamine reduces the extra biosynthesis and accumulation of a number of glucose metabolites, including glyceraldeyde-3-phosphate and dihydroxyacetone phosphate. Elevated levels of those glucose intermediates function as a trigger to most of the mechanisms accountable for hyperglycemia-caused cell damage. Benfotiamine increases tissue amounts of thiamine diphosphate, consequently growing transketolase activity and producing a significant decrease in glucose metabolites and precursors to AGEs. Up to now, two of the most effective AGE inhibitors in living microorganisms would be the Vitamin B1 derivative, benfotiamine and also the Vitamin B6 derivative, pyridoxamine. Additionally, benfotiamine has long been proven to lessen NF-kB activity, therefore restricting the over-production from the harmful superoxide toxin. Excess superoxide production may partly hinder a vital enzyme in glucose metabolic process, glyceraldehyde-3-phosphate dehydrogenase, directing glucose metabolites from glycolysis in to the major glucose-driven signaling paths that cause hyperglycemic damage. Theoretically, overdose with benfotiamine should cause menopausal flashes, bluish skin (because of rapid utilization of oxygen), tingling, and difficulty breathing, but used, this merely has not happened.
Kimia Biosciences Ltd™ is engaged in manufacturing of bulk drugs addressing to various high potential therapeutic segments and has envisaged high growth plans through infrastructure creation and CMS. Kimia has earmarked significant investment for this over next two years to become one of the major players in the Indian market. Moving forward towards vertical integration we have plans to set up our own FFF facilities for lifestyle segments with international regulatory standards to be able to not only launch itself in ROW but advance markets as well in future times. We envision becoming the most admired pharmaceutical company in India for clean and ethical business and marketing practices. We believe in maintaining the highest level of integrity, transparency and ethics. We embrace community values and culture and focus on delivering world class solutions at affordable costs.
Our Services:-
- Acotiamide Hydrochloride Hydrate
- benidipine hydrochloride
- Prucalopride Succinate
- Teneligliptin Hydrobromide Hydrate
- Ursodeoxycholic Acid
- Fimasartan Trihydrate Potassium
- Montelukast Sodium
- Phenylephrine HCL
Location:-974, Aggarwal Millennium Tower II, Netaji Subhash Place, Pitampura, New Delhi-110 034
Contact Number:-91-11-4706 3600
Email:-info@kimiabiosciences.com
Visit us:- http://kimiabiosciences.com
MitchellJohnson 